Small Angle Neutron Scattering revels the distribution of lipidic components in Lipid based nanoparticles, and how this is affected by serum protein binding

Lipid based Nanoparticles (LNPs) constitute a potent nanotechnology used in drug and gene delivery. Indeed, the Covid19 vaccines by Pziffer and Moderna use this technology. LNP efficiency, however, is low (as determined by the protein expression capacity per loaded RNA) and efforts are continuously being made to increase their potency. For example, improving the uptake […]

H2 loading induced reversible formation of graphitic domains in carbide-derived carbons

Carbon materials are used in a wide range of applications from gas filtration to energy storage in batteries and supercapacitors. Optimization and control of carbon structures, e.g. level of graphitization, is vital for achieving peak performance of these materials for a specific application. Thus far, the structure of carbon materials was primarily determined by the […]

Imaging/Tomography, 3 hp

This course targets masters, PhD students and possibly postdocs from all fields. The objectives of the course are to develop awareness and understanding of different neutron imaging methods and their possible applications in different areas of research. Students should thus be able to make more effective use of neutron imaging in research by identification of the […]

Post doctoral fellow in Polarised Small Angle Neutron Scattering

Lund University is seeking qualified candidates for a postdoctoral fellow position in a joint project with the European Spallation Source (ESS). The project focuses on developing innovative science using polarised small angle neutron scattering (SANS) and carrying out polarised neutron instrumentation work for the ESS SANS instruments LoKI and SKADI. In addition, the project also […]

Interplay of NH4+ and BH4- reorientational dynamics in NH4BH4

The reorientational dynamics can be linked to the occurrence of many interesting properties, e.g.  high ionic conductivities in M2BnHn and MCBn-1Hn (M = Li, Na; n = 10, 12). While most studies on reorientational dynamics have focused on compounds that contain one active species, new systems with interesting properties which exhibit dynamics on similar timescales […]

Effects of uniaxial pressure on the spin ice Ho2Ti2O7

Since the invention of the transistor and the photovoltaic cell, it has been clear that an understanding of emergent electronic and magnetic phenomena is of greatest importance for the development of modern society and sustainability. The low temperature properties of Ho2Ti2O7 has pusseled scientists for over two decades. The degenerate ground state of this material […]

Polymer composites: improving the environment, understanding scattering, and supporting enterprise

Plastic waste receives a lot of bad publicity but for some applications there are advantages for synthetic polymers over use of other materials.  Recycling is often readily practicable if the component materials are known, and so the balance of benefits and end-use costs needs to be carefully evaluated.  A recent study [1] came about from […]

Phase behaviour of ultrasoft spheres show stable bcc lattices

In order to rationally design new smart materials, it is pivotal to understand their phase behaviour. This means being able to predict under which conditions (e.g. temperature, pressure, concentration) such a material is a fluid, a disordered solid, or a crystal. Colloidal dispersions are suitable model systems to reproduce the behaviour of atomic systems and […]

Neutron reflection reveals how lipoproteins cannot exchange fats when both saturated fats and cholesterol are present in model membranes

We all have heard about the good and bad cholesterol and how these are affected by diet. Good cholesterol or high density lipoprotein (HDL) removes lipids from the vessels to get excreted in the liver. Bad cholesterol or low density lipoprotein (LDL) deliver lipids to the body. The truth is that both good and bad […]

How to tailor surfactant self-assembly in deep eutectic solvents using hydrotropes

While society strives towards more sustainable lifestyles, technological applications and products that use green solvents are coming up slowly. Deep eutectic solvents (DES) are the epitome of green neoteric solvents. They can be synthesised using simple and cheap organic precursors (e.g. polyols, carboxylic acids, amino acids…), where the mixture of two solid compounds at the […]

Bone nanostructure studied by small-angle neutron and X-ray scattering

Bone has remarkable mechanical properties resulting in a unique ability to withstand mechanical loading. It is a hierarchically structured composite material made up primarily of type-I collagen and hydroxyapatite (HAp) mineral. The combination of these constituents and their complex structural organisation, from the molecular level to the whole organ, result in a tissue with an […]

SwedNess PhD-students positions

SwedNess is a graduate school for neutron scattering operated by six of Sweden’s largest academic institutions/universities. The school is fully funded by the Swedish Foundation for Strategic Research (SSF) and aims to educate a new generation of highly skilled neutron experts. The research projects cover a broad range of scientific fields of high interest for both academia and […]

ILL PhD Studentships

A PhD project can be proposed by any academic researcher authorised to supervise PhD students and belonging to a university or affiliated institution in one of the ILL’s Associate or Scientific Member countries. If the PhD proposal is selected, the main proposer generally becomes the external academic PhD supervisor in whose university/institution the PhD student […]

SNSS Travel Grants

A limited number of grants per year will be available to promote the participation of bachelor and master students in experiments at large scale facilities for neutron scattering. Each grant consists of 10 000 SEK and will be used to cover transportation costs, accommodation, and meals. Read more…

Neutron scattering for medical and biomedical research, 1,5 hp

This course is an experimental part of cross-disciplinary course “MAX IV/ESS-based imaging for medical and biomedical research”. The main purpose of the course is to educate graduate students on the utilization of major neutron facilities. Lectures, presented by researchers from academia and neutron facilities, will include basic tutorials on the principles of scattering theory and […]

Measurement Methods and Radiation Detectors, 7.5 hp

The course provides theoretical and experimental knowledge of the detection of ionizing radiation and a good knowledge on measurement technique. The course covers the measurement of small currents and charges, pulse height analysis, statistics and deadtime corrections. Gas-, scintillation- and semiconductor detectors are treated, as well as neutron detectors etc. It also covers gamma spectroscopy […]

Structural biochemistry, 15 hp

The course aims to give insights into protein structure, how it can be modelled and experimentally determined. We start by discussing the forces that drive proteins to fold into three-dimensional structures. Then we look at different databases and discuss homology modelling, i.e. how one can model a protein’s three-dimensional structure if one knows the structure […]

Scattering methods, 7.5 hp

The aim of the course is for the student to acquire basic knowledge and understanding of different scattering methods used to study structural and dynamic properties of colloidal dispersions. The course begins with basic scattering theory, followed by a presentation of various experimental methods such as Small Angle Neutron Scattering (SANS), Small Angle X-Ray Scattering […]

Synchrotron- and Neutron based Experimental Methods and Applications, 15 hp

Purpose The course objective is for the student to develop an understanding of the theories for — as well as application, analysis and modelling of — experimental resources for synchrotron light and neutron radiation designs. Contents The course focuses on experimental methods and techniques available with synchrotron light and neutron radiation designs (such as ESS […]

Neutron Scattering, 10 hp

Neutrons offer a unique probe to address questions highly relevant to condensed matter research. In addition to the structure also the dynamics as well as magnetism can be studied. This is related to the characteristics of the neutron and the type of interaction with a sample differing from, e.g. x-rays or electrons. In this course […]

Quantum entanglement in low-energy neutron-proton scattering and its possible consequences

Hydrogen and compounds containing hydrogen are among the most frequently studied objects in neutron scattering. It is therefore important that the n-p scattering process is understood in detail for a correct interpretation of experimental data. The very high value for the bound proton cross section (σ = 81.9 barns) is caused by a specific feature […]

Grant for accessibility to infrastructure

The Swedish Research Council has been mandated by the Government to work towards ensuring researchers based in Sweden participate to a greater degree in the construction and development of research infrastructure, and towards making research infrastructure more accessible and more used by the business and public sectors. The Grant for Accessibility to Infrastructure is available to the […]

Effect of Formulation Method, Lipid Composition, and PEGylation on Vesicle Lamellarity: A Small-Angle Neutron Scattering Study

Liposomes are vesicles comprising a lipid membrane and aqueous core, and have found myriad applications in the biomedical field as therapeutics and in diagnostic assays. Liposome design requires careful choice of lipid composition and formulation method in order to produce populations with a defined unilamellar membrane structure. This is crucial in the development of liposome […]

Spontaneous Formation of Cushioned Model Membranes Promoted by an Intrinsically Disordered Protein

Histatin 5 is an intrinsically disordered, multifunctional, cationic, saliva protein known to act as the first line of defense against oral candidiasis caused by Candida albicans and belongs to the family of antimicrobial peptides. The mechanism at the base of its antifungal activity is still partially unknown. For this reason, understanding the interaction between Histatin […]

Apply for funding from Vinnova: Industrial pilot projects for utilisation of large-scale infrastructures for neutron and photon based techniques

  In this offer, we support project initiatives that build competence around industrial utilisation of advanced analytical techniques as those u at MAX IV and ESS. The proposals should be based on a need for at least one Swedish company and address verification regarding the suitability of the techniques to meet the need of the […]

Structure and composition of highly viscoelastic (α-CD)/anionic surfactant films investigated by neutron reflectivity

Understanding the surface rheological behavior of adsorbed films at the aqueous/air interface composed of sugars, surfactants, or complexes between them, is of great interest due to their relevance in different application areas ranging from food, medical diagnostics and oil recovery. Recently, we have found that α-cyclodextrin (α-CD)/anionic surfactant mixtures form films at the solution/air interface […]

Following protein dynamics in real time during crystallization

Diffraction from protein crystals remains the central pathway to high-quality protein structure determination, but a universal approach to crystallization has not been presented. This lack is linked to the underlying fundamental complexity of protein crystallization: proteins are nonspherical, flexible macromolecules with highly anisotropic interactions. Anisotropic sticky attraction can induce amorphous aggregation, and a better understanding […]

Local structure and vibrational dynamics of proton-conducting Ba2In2O5(H2O)x

Proton-conducting oxides are materials of huge interest for a variety of applications, such as electrolytes in membrane reactors or in proton-conducting fuel cells (PCFC) operating in the intermediate temperature range, T = 200 – 500°C. A limiting factor pertaining to the performance of present-day PCFC devices is a too low proton conductivity of the electrolyte […]

Producing matchout cholesterol for neutron scattering

The great advantage of using neutron scattering within the Life Sciences is not only the greater sensitivity towards hydrogen as compared to using X-rays as probe instead, but more importantly the ability to distinguish hydrogen from its heavier isotope deuterium.  This property enables highlighting different parts within a molecule or a molecular complex, and has […]

Understanding the structure of lipid sponge phase nanoparticle (L3-NPs) using small angle neutron scattering

Nonlamellar lipid liquid crystalline phases have many potential applications, such as for drug delivery, protein encapsulation or crystallization. Lipid liquid crystalline sponge phase (L3) has so far not been very much considered in these applications, in spite of apparent advantages in terms of its flexibility and capacity of forming large aqueous pores able to encapsulate […]

Tuning the alignment of nanocellulose using a magnetic field

Cellulose nanomaterials extracted from plants are very attractive due to their intrinsic optical and mechanical properties (e.g., high transparency, large elastic modulus, etc) and the potential novel applications that exploit these features. However, despite the extraordinary intrinsic properties of nanocelluloses at the nanoscopic level, the translation of the properties to the macroscopic level is not […]

Apply for funding via the new SAKURA Mobility Programme

To strengthen scientific collaboration between Sweden and Japan, the Swedish Research Council (VR) decided to fund and launch SAKURA, a new mobility programme focusing on neutron research and activities of ESS and J-PARC in particular. Personnel working at the two neutron sources as well as researchers affiliated with Swedish and Japanese universities are welcome to […]

GISANS revealed water influence on biobased thin films

Nanostructured porous thin films made from biocompatible cellulose nanofibrils (CNF) are widely used due to their attractive properties such as made from renewable resources, low density, lightweight, thermal stability, and excellent mechanical properties. These prerequisites make CNF a promising precursor for the design of bio composites and bio-inspired sensors. One crucial question is the relation […]

Polaris

The Polaris instrument at ISIS began operation as a high intensity, medium resolution powder diffractometer in the late 1980s. It quickly established a large and scientifically diverse research community, encompassing engineering, materials science, condensed matter physics, solid state chemistry and earth science. However, by the late 2000s many of the key components of the Polaris […]

Using inelastic neutron scattering to understand the local structure and vibrational dynamics in proton conducting oxides for sustainable energy technologies

Proton conducting oxides, and in particular acceptor doped BaZrO3, are materials of great interest because of their huge potential as electrolyte in several energy related technologies, such as hydrogen sensors, membrane reactors, steam electrolyzers, and intermediate-temperature (200 – 500 °C) solid oxide fuel cells. A key requirement for the electrolyte is a high proton conductivity […]

Interactions between Model Cell Membranes and the Neuroactive Drug Propofol

Many low molecular weight drugs, like classical surfactants, contain both hydrophobic and hydrophilic groups. However, due to their lower molecular weight and less distinct separation into hydrophobic and hydrophilic regions, the self-assembly of such drugs in aqueous solutions is less easy to describe in general terms. To gain more understanding of the interaction between such […]

How AstraZeneca can improve lipid nanoparticle formulations for gene delivery using neutron scattering

In recent year, new therapeutic modalities involving delivery of biological molecules such as RNA, peptides and oligonucleotides have shown promising results to treat diseases that are currently hard to tackle with standard small molecules approaches. As an example, last year Alnylam announced the first therapy using small interference RNA (siRNA) approved by the Federal Drug […]

Neutrons used to probe magnetism in three dimensional magnetic data storage elements

The transition from the current two-dimensional data storage and logic schemes to three-dimensional data structures could significantly improve the performance and capacity of electronic devices. Instead of simply storing and manipulating data in a two-dimensional array of elements, one can envisage stacking data bits on top of each other, thus greatly enhancing the data density. […]

Swelling of Thin Graphene Oxide Films Studied by in Situ Neutron Reflectivity

Multilayered Graphene Oxide (GO) materials such as membranes and thin films are known for their potential for selective ion permeation, nano-filtration, water desalination and gas barrier properties. Many recent studies have aimed at demonstration of selective permeation of certain ions and molecules through GO membranes. Membrane tests were demonstrated to be successful for relatively thin […]

Are you our new Webmaster?

The Swedish Neutron Scattering Society (SNSS) is searching for a webmaster/webdesigner. We are searching for a motivated student to further develop and keep the society’s webpage up to date. The student must be registered at one of the following universities: Chalmers Technical University Uppsala University KTH Linköping University Lund University Malmö University Besides further implementing […]

Using neutron reflectivity to elucidate electro-responsiveness of interfacial layers of ionic liquids and their solutions

Ionic liquids (ILs) have been identified as promising replacements for conventional lubricants. Their ionic nature and wide electrochemical windows present a new horizon for electrical energy storage solutions and tribotronic lubrication, whereby the friction coefficient is controllable though use of an electric field. However, due to the high production costs the commercialisation of IL lubricants […]

Structure and Dynamics of Non-Lamellar Lipid Bilayers at Interfaces, Implication in Biomembrane Organisation and Drug Delivery Applications

Lipids are the main components of cellular membranes. The main building blocks of the membranes that surround cells are lipid mixtures that form lamellar phases. However, lipids have a rich phase behaviour ranging from micellar, hexagonal or cubic to lamellar and, further, to the reversed counterparts, which are also utilised in many biological systems. The […]

Seeing the lithium inside your phone – Neutron scattering to follow real-time processes in energy storage devices

Rapid growing demands on electric-power based automotive transportation, grid applications and electronic devices require development of sustainable rechargeable batteries. This also arises from an urgent need to decrease CO2 emissions and to implement renewable energies into society. Unfortunately, improvements to battery materials has been slow and discovery of new materials with improved properties even slower. […]

The Swedish Research Council’s Grant for Accessibility to Infrastructure

The logos of The Swedish Research Council, SciLifeLab, MAX IV, and ESS.

The Swedish Research Council has been mandated by the Swedish Government to work towards ensuring Swedish researchers participate to a greater degree in the construction and development of research infrastructure, and towards making research infrastructure more accessible and more used by the business and public sectors. Type of call Research infrastructure support Subject area Research […]

Neutron scattering aids in understanding atherosclerotic plaque build-up – a game of hide and seek

Experimental set-up

Why is it so that individuals with good cholesterol values develop cardiovascular disease, whilst other individuals with poor values remain healthy? Cholesterol and other fats are transported through the blood via specific transporters called lipoproteins. The most well-known are the so called “good” and “bad” cholesterol. Understanding these particles in structure and composition and the way they interact with artery wall is crucial in understanding this disease, the main killer of the West. Such knowledge would aid in improving diagnostic tools as well as in development of new drugs.

SNSS announces support of the Swedish Research Council’s call to register interest in future in-kind contributions to the ESS

SNSS supports the Swedish Research Council’s effort to invite universities to suggest possibilities for in-kind involvement towards ESS, and to promote increased interaction between Swedish universities as well as towards industry. For additional information please see the PDF document below or click this link (in Swedish only).

Industrial pilot projects for neutron and photon experiments in large scale research infrastructures

In this call notice, Vinnova announces their financial support for pilot projects that build expertise on industrial utilization of advanced experimental environments similar to those developed at MAX IV and ESS in Lund. The work in the project will be verified of how neutron or photo technique is suitable for meeting a company’s problems or development needs.

Neutrons to study the interplay between aquaporins and porous silica in water treatment

Professor Martin Andersson (Chalmers) — Today, water purification typically includes a size-exclusion based filter that is specialized in removing a certain number of common water pollutants. But these filters do not remove all the pollutants present in water. So why not develop a filter that produces clean water regardless of pollutant? Guess what – nature already did.

SNSS researcher Dr. Selma Maric is awarded The Camurus Lipid Research Foundation Junior Prize

Dr Selma Maric

The Swedish Neutron Scattering Society is proud to announce that Dr. Selma Maric, one of our very own researchers, is one of the recipients of The Camurus Lipid Research Foundation Junior Prize 2018. Since receiving her PhD in biophysics 2014 at the Niels Bohr Institute (University of Copenhagen), she has held post-doc positions at the Karolinska Institute and […]

MATRAC 2 Winter School

We take pleasure in informing you that registration is now open (Deadline 1 Dec. 2016!!!) for the MATRAC 2 Winter School ‘Application of Neutrons and Synchrotron Radiation in Materials Science with special focus on Fundamental Aspects of Materials’ to be held in Utting/Ammersee and Garching/Munich, Germany, February 27 to March 3, 2017.

SNSS annual meeting 2016

The next annual meeting for SNSS will be held in Lund in late spring 2016. The meeting is planned as a lunch-to-lunch meeting, 30th/31st May 2016. The meeting is organised back-to-back with the  Neutrons and Food conference and on the afternoon of 31st May the two meetings will be bridged with a tour of the ESS […]

News 2014

2014-12-17 SNSS Newsletter 2014 As the year is ending we are sending out some information to all members of SNSS. The newsletter is available here. We wish you a Merry Christmas and a Happy New Year! 2014-07-04 !!! ESS Gets the Green Light !!! On July 4, 2014 the Swedish Minister of Education and Research […]